Protein folding: Versatility of the cytosolic chaperonin TRiC/CCT

نویسندگان

  • Michel R. Leroux
  • F.Ulrich Hartl
چکیده

Efficient de novo folding of actins and tubulins requires two molecular chaperones, the chaperonin TRiC (or CCT) and its novel cofactor GimC (or prefoldin). Recent studies indicate that TRiC is exquisitely adapted for this task, yet has the ability to interact with and assist the folding of numerous other cellular proteins.

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عنوان ژورنال:
  • Current Biology

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2000